GLaDOS is the funniest character in games and she spends the whole time calling you fat and stupid.
Fun fact: Began development as a prequel called "F-STOP" that had no portals at all.
Been on so long that the early seasons are genuinely funnier than most actual comedies that tried.
Fun fact: Matt Groening named Homer, Marge, Lisa, and Maggie after his own parents and sisters.